Manipulating the rate of memory CD8+ T cell generation after acute infection

VP Badovinac, JT Harty - The Journal of Immunology, 2007 - journals.aai.org
… monocytogenes infection of mice that were pretreated with antibiotics resulted in reduced
expansion of Ag-specific CD8 T cells, but the generation of long-term memory CD8 T cells

Programming, demarcating, and manipulating CD8+ Tcell memory

VP Badovinac, JT Harty - Immunological reviews, 2006 - Wiley Online Library
manipulate and accelerate generation of CD8 + T cells with … define long-term memory CD8
+ T cells after acute infection? … which primary memory CD8 + T cells will expand, and the level

Shaping and reshaping CD8+ T-cell memory

JT Harty, VP Badovinac - Nature Reviews Immunology, 2008 - nature.com
T cells have a crucial role in generating optimal CD8 + T-cell … are cleared (acute infection),
memory CD8 + T cells are maintained … Using this definition, 40–60 days after acute infection or …

CD4+ T cells are required for the maintenance, not programming, of memory CD8+ T cells after acute infection

JC Sun, MA Williams, MJ Bevan - Nature immunology, 2004 - nature.com
… day-100 memory CD8 + T cells specific for GP(33–41) (using anti-… (c,d) Percentage of memory
CD8 + T cells in MHC class II–… an acute infection, the generation of memory CD8 + T cell

Memory CD8 T-cell differentiation during viral infection

EJ Wherry, R Ahmed - Journal of virology, 2004 - Am Soc Microbiol
… To address this question directly using labeled cells that could … , culminating in the generation
of effector CD8 T cells and viral … If the level or frequency of antigenic stimulation of T cells is …

[HTML][HTML] Dendritic cells maximize the memory CD8 T cell response to infection

DJ Zammit, LS Cauley, QM Pham, L Lefrançois - Immunity, 2005 - cell.com
… for the initiation of a primary CD8 T cell response have been … requirements for generating a
memory CD8 T cell recall … that other cells types could drive some level of CD8 memory T cell

Memory CD8 T-cell compartment grows in size with immunological experience

V Vezys, A Yates, KA Casey, G Lanier, R Ahmed… - Nature, 2009 - nature.com
after primary infections that result predominantly in the generation of central memory CD8 T
cells… So far, clinical vaccine trials using CD8 T cells have failed to protect against HIV 20,21 . …

Shortening the infectious period does not alter expansion of CD8 T cells but diminishes their capacity to differentiate into memory cells

MA Williams, MJ Bevan - The Journal of Immunology, 2004 - journals.aai.org
… cytokine expression using reagents provided in the … of memory CD8 T cells in ampicillin-treated
mice to persist long-term, we analyzed the generation and maintenance of memory cells

[HTML][HTML] Influence of time and number of antigen encounters on memory CD8 T cell development

MD Martin, VP Badovinac - Immunologic research, 2014 - Springer
… On the cellular level, memory CD8 T cells may begin to … ] examined memory CD8 T cell
generation in response to infectionUsing the serial adoptive transfer model, we reported that the …

Antigen-independent memory CD8 T cells do not develop during chronic viral infection

EJ Wherry, DL Barber, SM Kaech… - Proceedings of the …, 2004 - National Acad Sciences
… chronic infection by using the mouse model of infection with … in the percentage of CD62L
Hi acute memory CD8 T cells (P … , resulting in the generation of memory CD8 T cells that have …